Serum levels of chemical elements and carious lesions in children after antitumor therapy

Aim. To study serum concentrations of trace and macro elements their correlations in children adolescents after antitumor therapy, depending on the presence or absence caries. Materials methods. The included 98 patients aged 4 to 17 years who were remission an therapy performed for acute leukemia lymphomas. Patients with carious tooth lesions group 1 ( n = 34) without caries – 2 64). We used inductively coupled plasma mass spectrometry calculate content essential, conditionally essential toxic blood serum. median interquartile range calculated, Mann-Whitney U -test was applied compare groups, Kendall rank correlation coefficient (τ) calculated tandem elements. Results. In both studied within reference ranges. 1, compared 2, higher potassium, arsenic, iodine boron lower lithium tungsten p < 0.05) noted. There no differences concentration phosphorus, calcium, magnesium, manganese, gold, silver, platinum, aluminum, beryllium, bismuth, cadmium, cobalt, chromium, copper, iron, mercury, lithium, molybdenum, nickel, rubidium, antimony, tin, vanadium, zinc, zirconium thallium between groups. Significant coefficients groups obtained iron/manganese (τ 0.24, 0.05). Different values τ got nickel/ cobalt/iron, manganese/phosphorus, beryllium/lithium tandems: 0.342 0.14; 0.363 0.033; –0.111 –0.326; –0.365 0.42, respectively, 2. Conclusion. association increase (within values) (potassium, iodine) (arsenic, boron), a decrease tungsten; as well change ratio nickel/manganese, manganese/ phosphorus direction revealed.